We try to constantly keep our readers up to date on all the latest information when it comes to turmeric. In recent months, there has been an elevated interest in liposomes and how they can help supplements by increasing their bioavailability. Since we get a lot of questions regarding what inspired us to create our new Turmeric Liposome Complex, we thought we’d share studies about liposomal turmeric and why we were inspired to step up our game and create the best turmeric supplement out there!
International Journal of Nanomedicine
The article, “Liposomal curcumin and its application in cancer” was one of the first articles to pique our interest in adding liposomes to our turmeric product. The article discusses how some plant extracts have shown interesting anticancer properties without the serious side effects of cytotoxic agents. Among them, curcumin. However, with the challenge of low bioavailability and rapid systematic elimination, it wasn’t as effective as it could be until liposomal technology was introduced.
Colloids and surfaces. B, Biointerfaces
“Assessing the potential of liposomes loaded with curcumin as a therapeutic intervention in asthma” is an article that appeared in Colloids and surfaces. B, Biointerfaces in December 2018. What is interesting about this article is its focus on asthma in particular. Traditional therapies address controlling disease symptoms by using inhalers and other corticosteroids. Unfortunately, long-term use of these therapies can introduce their own problems for users. Researchers looked at options that can address asthma without the side effects. Curcumin, an anti-inflammatory, was considered, but the challenge was the low bioavailability and hence limits its application. Curcumin-loaded liposomes formulation resulted in significant reduction in the level of pro-inflammatory marker expression compared to positive control group. A very promising result for asthma sufferers!
International Journal of Experimental and Clinical Pathophysiology and Drug Research
Due to the fact that curcumin is poorly soluble in water, many delivery systems have been developed to improve its solubility and bioavailability achieving optimum therapeutic application. In this study, which was presented in the article, “Toxicity and Biological Activity in Synovial Fibroblasts and Macrophages” they evaluated the biological effects of a liposomal curcumin formulation. Data showed that the liposomal curcumin formulation was significantly less toxic to synovial fibroblasts and macrophages compared to non-encapsulated, free curcumin.
International Journal of Cancer Research and Treatment
In the article, “Efficacy of Liposomal Curcumin in a Human Pancreatic Tumor Xenograft Model: Inhibition of Tumor Growth and Angiogenesis” the abstract states that liposome-based drug delivery has been successful. The major disadvantage associated with curcumin, a potent anticancer agent, is its poor aqueous solubility and hence low systemic bioavailability. However, curcumin can be encapsulated into liposomes to improve systemic bioavailability. They determined the antitumor effects of a liposomal curcumin formulation against human pancreatic cancer cells both in vitro and in xenograft studies, observing that designing a nanoparticle-based drug delivery system that enhances the solubility of curcumin in an aqueous phase medium may significantly improve its potential clinical applications.
There are several more articles and studies about liposomal turmeric, but the bottom line is this: liposomal turmeric is more bioavailable and therefore more readily used by your system because the absorption rate is increased. As always, it’s important to look for turmeric products that not only leverage liposomes but are organic and made in the USA to ensure you’re getting the highest quality supplement available.